Developing superior research and innovation to increase the competitiveness of rural resources and local wisdom is one of the main mandates to achieve the university's vision in 2034. The results of research work cover seven priority areas, namely:

• Tropical Biodiversity and Bioprospecting
• Marine, Coastal, and Inland Management
• Food, Nutrition, and Health
• New and Renewable Energy
• Entrepreneurship, Cooperation, Micro & Small-Scale Enterprise
• Social Engineering, Rural Development and Community Empowerment
• Basic Science and Engineering

Opening free digital access to public is expected to accelerate the transfer of information and technology that has been produced by campus researchers and academics, so that it can provide wider benefits for the nation’s development. This could count as a form of accountability to society. The researches’ results by researchers at Universitas Jenderal Soedirman are published in journals. One of the online journal platforms is Jurnal Online Soedirman (Jurnal Online Soedirman)